Disruption

Chronic Circadian Disruption

Classified a probable carcinogen. The most serious, most overlooked circadian harm.

DisruptionIARC Group 2A (probable carcinogen)

Acute Circadian Desynchrony

Eastward is harder than westward. The clock re-syncs about one hour per day.

DisruptionMelatonin/light evidence-based

The Hormone of Darkness

Not a sleeping pill, a darkness signal. And most people take 10x too much.

HormoneOTC supplement (US); Rx in EU

Seasonal Affective Disorder (SAD) · Circadian Mood Disruption

Recurrent winter-pattern depression tied to a delayed circadian clock, not the same thing as the winter blues.

Circadian-Linked Mood DisorderNo drug approved specifically for SAD; light boxes are unregulated wellness devices, not FDA-cleared for SAD. Bupropion XL is FDA-approved for SAD prevention.

Evening Light Exposure & Devices

The wavelength gets the blame, but brightness, and what you do on the screen, matter more.

DisruptionConsumer products vary

Weekday-Weekend Clock Mismatch

Living on two time zones at once, your body's and your alarm's. Most people have it.

DisruptionChronobiology concept

Schedules, Meals & Social Rhythm

Regular social rhythms anchor the clock, and stabilizing them treats mood disorders.

ZeitgeberBehavioral science