Probiotics' Best-Evidence Use Case
Preventing diarrhea caused by antibiotics is the strongest, best-evidenced use of probiotics, with specific strains clearly ahead.
Probiotics
How they work, gut-brain, SCFAs
11 entries. 6 rest on strong human evidence. Ordered with the best evidenced first.
Probiotics' Best-Evidence Use Case
Preventing diarrhea caused by antibiotics is the strongest, best-evidenced use of probiotics, with specific strains clearly ahead.
Whole-Food Fermentable Fiber Sources
Chicory, garlic, onion, green banana, oats, legumes. Feed the bacteria you already have.
Fermentable Fibers That Feed the Microbiome
You cannot out-supplement a bad diet. Prebiotics feed the bacteria you already have.
Butyrate, Propionate & Acetate
The real output of the microbiome. Butyrate fuels your colon and quiets inflammation.
Why "Probiotics" Is the Wrong Question
The most important and most ignored fact in probiotics: effects are strain-specific and disease-specific, not a general "probiotic" property.
Do Probiotics Even Stick Around?
Most probiotics do not permanently colonize the gut, they pass through, and that reframes how they could possibly work.
Refrigeration & Probiotic Viability
Refrigeration signals formulation quality, not viability at the moment you swallow it.
Microbiome-Nervous System Communication
The microbiome talks to the brain. 90% of serotonin is made in the gut.
Beneficial Bacterial Metabolites & Components
The benefit without the live bacteria. Butyrate, urolithin A, equol, heat-killed cells.
Bacillus Endospore-Forming Bacteria
Heat- and acid-proof bacteria that survive where Lactobacillus dies. The survivability category.
Lactobacillus & Bifidobacterium
The dominant category, decades of evidence, native to the human gut, and fragile by nature.