N-Acetylcysteine · Cysteine / Glutathione Precursor
Pharmaceutical-grade glutathione precursor that briefly disappeared from US supplement shelves, and came back.
Supplements
Heart & Metabolism
Cardiovascular, lipids, inflammation
19 products. 1 rest on strong human evidence. Ordered with the best evidenced first.
19 products in Heart & Metabolism
α-Lipoic Acid · Thioctic Acid · The Universal Antioxidant
A German prescription drug for diabetic neuropathy, a US supplement for metabolic health.
Berberine · Isoquinoline Alkaloid · "Nature's Ozempic" (Misleading) · AMPK Activator
Isoquinoline alkaloid · metformin-comparable HbA1c · "Nature's Ozempic" viral framing · substantial drug-supplement boundary.
Boswellia serrata / Indian Frankincense Resin Extract
The 5-LOX inhibitor anti-inflammatory, distinct mechanism from NSAIDs.
Coenzyme Q10 · Ubidecarenone · Mitochondrial Electron Carrier
The mitochondrial cofactor with the cleanest heart-failure meta-analysis of any supplement.
Curcumin / Curcuminoid Standardized Extract (Curcuma longa)
The substantial anti-inflammatory polyphenol, formulation matters substantially.
Grape Seed Extract · Vitis vinifera OPC · Endotelon Heritage
The cost-effective OPC alternative with wine industry sustainability and European pharmaceutical heritage.
L-Arginine · The Original NO Substrate
The original nitric oxide substrate, largely supplanted by L-citrulline in modern supplement protocols.
L-Citrulline · The Watermelon Amino Acid
The watermelon amino acid that delivers L-arginine's benefits without L-arginine's pharmacokinetic problem.
Fish-Oil Polyunsaturated Fatty Acids
The classic case of observational positive, randomized null, at supplement doses.
Menaquinone-7 (MK-7) · Menaquinone-4 (MK-4)
Strong mechanism, maturing outcome evidence, and the form really does matter.
A. muciniphila · The Mucin-Degrading Symbiont
Next-generation probiotic, the mucus-layer symbiont with metabolic-health emerging evidence.
Ginkgo biloba · The Living Fossil · EGb 761
Living fossil with two centuries of medical use, and two major modern trials that failed to prevent dementia.
Pycnogenol · French Maritime Pine Bark Extract (Horphag)
The single-source branded OPC, premium-priced for substantial brand-specific clinical evidence inheritance.
Quercetin · The Flavonol Mast Cell Stabilizer
The natural antihistamine that works through a different mechanism than the pharmaceutical one.
Trans-Resveratrol · The Sirtuin Sirtris Story
The longevity headliner whose mechanism story was bigger than the clinical translation.
Schisandra chinensis · Wu Wei Zi · The Five-Flavor Berry
The five-flavor berry with parallel Chinese hepatic and Soviet performance research traditions.
2-Aminoethanesulfonic Acid · The Ox-Bile Amino Acid
From ox bile to energy drinks to longevity science, and a real Japanese cardiology heritage in between.
Curcuma longa · Haridra · Curcuminoids
Four thousand years old, a real anti-inflammatory, and a formulation puzzle.