1,3,7-Trimethylxanthine · The World's Most Consumed Stimulant
The world's most consumed psychoactive, with the cleanest performance evidence of any stimulant.
Supplements
Daily Foundation
Everyday baseline nutrition
36 products. 8 rest on strong human evidence. Ordered with the best evidenced first.
36 products in Daily Foundation
Creatine Monohydrate · The Phosphocreatine Buffer
The most-validated sports supplement, expanding into brain and longevity.
Folic Acid · 5-MTHF · Vitamin B9
Among the highest-evidence interventions in all of nutrition.
Cobalamin · Methyl, Cyano, Hydroxo, Adenosyl
Foundational, cohort-dependent, and the form debate is smaller than getting enough.
Ascorbic Acid · Water-Soluble Antioxidant
The cleanest reference supplement, settled, modest, real.
Cholecalciferol · Fat-Soluble Hormone-Vitamin
The most-tested supplement on Earth, strongest in deficiency, modest in replete adults.
N-Acetyl-5-Methoxytryptamine · Pineal Hormone
A real hormone, sold like a supplement, dosed ten times higher than the physiology suggests.
Essential Trace Mineral
A real immune mineral with a narrow window, more is not better.
Withania somnifera · Ayurvedic Rasayana
Most-researched adaptogen of the modern era, with the cortisol data to back it up.
Berberine · Isoquinoline Alkaloid · "Nature's Ozempic" (Misleading) · AMPK Activator
Isoquinoline alkaloid · metformin-comparable HbA1c · "Nature's Ozempic" viral framing · substantial drug-supplement boundary.
Boswellia serrata / Indian Frankincense Resin Extract
The 5-LOX inhibitor anti-inflammatory, distinct mechanism from NSAIDs.
Cannabidiol · Phytocannabinoid · FDA-Approved Epidiolex Drug + Dietary Supplement
Phytocannabinoid · FDA-approved epilepsy drug · disputed supplement status · substantial M-05 regulatory whiplash.
Hydrolyzed Collagen · Type I, II, III · Bioactive Peptides
A massive market with a real branded-peptide story underneath the marketing.
Curcumin / Curcuminoid Standardized Extract (Curcuma longa)
The substantial anti-inflammatory polyphenol, formulation matters substantially.
Magnesium Citrate · Form-Factor Sibling
A two-for-one, magnesium supplementation when low-dose, GI relief when high.
Fish-Oil Polyunsaturated Fatty Acids
The classic case of observational positive, randomized null, at supplement doses.
Panax ginseng · Asian Ginseng · Korean Red Ginseng
The "all-healing" panacea root with two millennia of Korean tradition and substantial modern clinical evidence, and substantial adulteration concerns.
Single-Brand Foundational Daily Greens Powder
The original influencer-economy daily greens, and the consumer category it created.
Conditionally Essential Trace Mineral
Conditionally essential, and most Western diets fall short of the dose range with benefit evidence.
Eleutherococcus senticosus · "Siberian Ginseng" · The Cold War Adaptogen
Cold War-era Soviet performance research repackaged as Siberian ginseng, and prohibited from that name in the EU since 2003.
Glucosamine Sulfate + Chondroitin Sulfate · Joint Building Blocks
The most-purchased joint supplement, with a famously divided evidence base.
Centella asiatica · Brahmi (Ayurvedic) · Indian Pennywort
The Ayurvedic cognitive herb confused with Bacopa, and a substantial European microcirculation tradition.
Ocimum sanctum · Tulsi · The Queen of Herbs
Three thousand years of Ayurvedic veneration meets modest modern stress evidence.
Sodium Hyaluronate · Hyaluronan · The Water-Binding Polymer
The water-binding polymer that fills nearly every interstitial space, and a recent oral category with modest evidence.
Magnesium Bisglycinate Chelate
The reference form of magnesium, high absorption, easy on the gut.
Silybum marianum · Silymarin · St. Mary's Thistle
Two thousand years of liver-protective tradition, meeting modern bioavailability and clinical trial reality.
Pycnogenol · French Maritime Pine Bark Extract (Horphag)
The single-source branded OPC, premium-priced for substantial brand-specific clinical evidence inheritance.
Quercetin · The Flavonol Mast Cell Stabilizer
The natural antihistamine that works through a different mechanism than the pharmaceutical one.
Seed DS-01 Daily Synbiotic · 24-Strain Probiotic + Prebiotic Polyphenols
The science-positioning DTC probiotic synbiotic, substantial transparency, advisory framework, sustainability.
Silicon Dioxide · From Horsetail (Equisetum arvense)
An ancient plant's silicon mineral content, modest evidence, mechanistically coherent.
Spermidine / Polyamine (Wheat Germ, Soy, Aged Cheese)
The autophagy-inducing polyamine, substantial longevity research framework.
2-Aminoethanesulfonic Acid · The Ox-Bile Amino Acid
From ox bile to energy drinks to longevity science, and a real Japanese cardiology heritage in between.
Valeriana officinalis · The Sleep Root
Two thousand years of sleep tradition, modest modern evidence, real GABA-A mechanism.
Bloom Greens & Superfoods · Mari Llewellyn · Nestlé Health Science
The viral TikTok answer to AG1, accessibly priced, flavored, mass-market retail.
Huel Daily Greens · UK Plant-Based Multi-Ingredient Greens · 91 Ingredients
The European maximalist plant-based answer to AG1, 91 ingredients, mushroom-integrated.
Live It Up Daily Greens · Plant-Based Multi-Greens Powder
The focused-minimalist plant-based greens DTC alternative in the AG1 framework.