Creatine Monohydrate · The Phosphocreatine Buffer
The most-validated sports supplement, expanding into brain and longevity.
Supplements
Longevity
Cellular aging, healthspan
20 products. 3 rest on strong human evidence. Ordered with the best evidenced first.
20 products in Longevity
Alpha-Tocopherol · Mixed Tocopherols
The textbook observational-versus-randomized reversal.
N-Acetylcysteine · Cysteine / Glutathione Precursor
Pharmaceutical-grade glutathione precursor that briefly disappeared from US supplement shelves, and came back.
α-Lipoic Acid · Thioctic Acid · The Universal Antioxidant
A German prescription drug for diabetic neuropathy, a US supplement for metabolic health.
Hydrolyzed Collagen · Type I, II, III · Bioactive Peptides
A massive market with a real branded-peptide story underneath the marketing.
Coenzyme Q10 · Ubidecarenone · Mitochondrial Electron Carrier
The mitochondrial cofactor with the cleanest heart-failure meta-analysis of any supplement.
Curcumin / Curcuminoid Standardized Extract (Curcuma longa)
The substantial anti-inflammatory polyphenol, formulation matters substantially.
Grape Seed Extract · Vitis vinifera OPC · Endotelon Heritage
The cost-effective OPC alternative with wine industry sustainability and European pharmaceutical heritage.
A. muciniphila · The Mucin-Degrading Symbiont
Next-generation probiotic, the mucus-layer symbiont with metabolic-health emerging evidence.
Apigenin / 4',5,7-Trihydroxyflavone (Parsley, Celery, Chamomile)
The dietary flavonoid with senolytic and sleep-modulating positioning.
Conditionally Essential Trace Mineral
Conditionally essential, and most Western diets fall short of the dose range with benefit evidence.
Ginkgo biloba · The Living Fossil · EGb 761
Living fossil with two centuries of medical use, and two major modern trials that failed to prevent dementia.
Sodium Hyaluronate · Hyaluronan · The Water-Binding Polymer
The water-binding polymer that fills nearly every interstitial space, and a recent oral category with modest evidence.
Silybum marianum · Silymarin · St. Mary's Thistle
Two thousand years of liver-protective tradition, meeting modern bioavailability and clinical trial reality.
Methylsulfonylmethane · Dimethyl Sulfone · Organic Sulfur Donor
A sulfur donor with modest evidence for joint comfort and exercise recovery.
Nicotinamide Mononucleotide · NAD+ Precursor
The flagship longevity supplement of the 2020s, and the most commercially conflicted.
Pterostilbene · The Methylated Resveratrol with 80% Bioavailability
What resveratrol would be if pharmacology actually translated.
Trans-Resveratrol · The Sirtuin Sirtris Story
The longevity headliner whose mechanism story was bigger than the clinical translation.
Spermidine / Polyamine (Wheat Germ, Soy, Aged Cheese)
The autophagy-inducing polyamine, substantial longevity research framework.
2-Aminoethanesulfonic Acid · The Ox-Bile Amino Acid
From ox bile to energy drinks to longevity science, and a real Japanese cardiology heritage in between.